Peg-12 Dimethicone : Safe Application In Cosmetics

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    PEG-12 Dimethicone    is a PEG combined with polydimethylsiloxane (polydimethylsiloxane), which is an organosilicon-based polymer that can be formulated Smooth, promote spreadability and increase lubricity. It can be used as a surface tension inhibitor, hair conditioner, skin conditioner, wetting agent, emulsifier and foaming agent (source) in a variety of beauty products and cosmetics. Due to the low molecular weight of PEG 12 dimethicone, skin absorption is minimal.

    Although there are many concerns about PEG, due to their different characteristics, they are regarded as ingredients of a large number of products. A study published in the Journal of Toxicology in 2005 entitled "Safety Assessment of Polyethylene Glycol (PEG) and Its Derivatives Used in Cosmetics" concluded that: "Considering all relevant aspects of this compound Available information, and the safety of these endpoints cannot be determined based on the mode of action and mechanism of action, therefore, the conclusions drawn from the existing data are that PEG and its ether (lauryl) base with a wide molecular weight range (200 to 10,000 or more) Cetyl, cetearyl stearate, stearate and fat) and fatty acid esters (laurate, dilaurate, stearate, stearate) can be used safely In cosmetics."

    PEG 12 dimethicone is not considered an irritant or sensitizer. Approved by CIR and FDA can be used for skin, but not for damaged skin.


    The cosmetics database found that PEG 12 dimethicone has moderate hazards (depending on usage), and pay attention to pollution and toxicity issues.

    According to a study published in the International Journal of Toxicology, PEG (including PEG 12 Dimethicone) may contain harmful impurities, including: ethylene oxide, based on experimental results, it is known to increase uterine cancer and breast cancer and The National Toxicology Program reports the incidence of leukemia and brain cancer; 1,4-dioxane, a known carcinogen; PAHs, known to increase the risk of breast cancer; lead; iron; and arsenic (source) .

    Products and formulations containing PEG must not be used on damaged or irritated skin. Although PEG is considered safe for topical use on healthy skin, studies have shown that patients with severe burns have been treated with PEG-based antibacterial cream; this treatment results in kidney toxicity. "It was determined that the PEG content of the antimicrobial cream was the cause. However, in the skin integrity study, there was no evidence of systemic toxicity. Due to the observed kidney effects of burn patients, the CIR expert team identified their conclusions. The safety of the PEG component Sex, indicating that cosmetic preparations containing these ingredients should not be used on damaged skin"

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