Interaction with Buffs (Sisters of Garukhan)
The Sisters of Garukhan encounter, when completed, grants you a +10% Lightning Resistance buff. This buff is particularly useful in Path of exile currency counteracting the -10% Lightning Resistance debuff that you receive after completing Act 1.
However, after completing Act 2, you’ll face a -20% Lightning Resistance debuff. If you complete the Sisters of Garukhan encounter again, you’ll get an additional +10% Lightning Resistance, bringing your net Lightning Resistance to -10% (i.e., still below neutral).
Why It Can Be Confusing
Visible Resistances: After interacting with the Sisters of Garukhan shrine and receiving the +10% Lightning Resistance buff, you may still see negative Lightning Resistance on your resistances menu due to the cumulative debuff.
Example: If you activate the shrine in Act 2 (with a -10% Lightning Res debuff from Act 1) and then proceed to Path of exile currency for sale Act 2 Cruel (which adds another -10% debuff), you’ll see a net -40% Lightning Resistance unless you've activated the Sisters shrine again, in which case it would be -30%.